SACCHETTINI, JAMES C.,MILLER, MATTHEW W.,WALLIS, DEEANN,ZHOU, NIAN E.,FOSSUM, THERESA W.
申请号：
CA2940140
公开号：
CA2940140A1
申请日:
2015.02.19
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
Compositions and methods for inhibiting and/or sensitizing or re-sensitizing a parasite to an antiparasitic drug are provided. The compositions can comprise a rifamycin derivative or a pharmaceutically acceptable salt, hydrate, or prodrug thereof in an amount and formulation sufficient to inhibit or induce drug-sensitization in a parasite. The methods can comprise administering a rifamycin derivative or a pharmaceutically acceptable salt, hydrate, or prodrug thereof to a parasite in an amount and formulation sufficient to inhibit or induce drug-sensitization in the parasite.
