Seok-Ki Choi,Paul R. Fatheree,Robert Murray McKinnell,Brooke Olson
申请号:
US13483399
公开号:
US08513432B2
申请日:
2012.05.30
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The invention relates to compounds having the formula:wherein Ar, r, n, X, R2, R2′, R3, and R5-7 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have AT1 receptor antagonist activity and neprilysin inhibition activity. The invention also relates to pharmaceutical compositions comprising such compounds methods of using such compounds and a process and intermediates for preparing such compounds.