Seok-Ki Choi,Paul R. Fatheree,Roland Gendron,Ryan Hudson,Robert Murray McKinnell,Vivek Sasikumar
申请号：
US12898999
公开号：
US08106082B2
申请日:
2010.10.06
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention relates to compounds having the formula:wherein: Ar, r, R3, Z, X, and R5-7 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have AT1 receptor antagonist activity and neprilysin inhibition activity. The invention also relates to pharmaceutical compositions comprising such compounds methods of using such compounds and process and intermediates for preparing such compounds.
