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Aurora kinase inhibitors from an encoded small molecule library
专利权人:
Matthew Clark
发明人:
Matthew Clark
申请号:
US12375164
公开号:
US08138338B2
申请日:
2007.07.27
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention provides, at least in part, compounds of formula (I): or a pharmaceutically acceptable salt thereof, wherein Z1, Z2, Z3, R1, x, y, R2, R3, R4a, R4b, R5, R6 and R7 are described herein, as well as methods for their identification, their preparation, pharmaceutical compositions containing them, and their use as Aurora A kinase inhibitors in treatment, e.g., of cancer and other proliferative disorders.
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