Sreenivasu Mudumba,Philippe J M Dor,Thierry Nivaggioli,David A. Weber,Sidiq Farooq
申请号：
US14553947
公开号：
US09381153B2
申请日:
2014.11.25
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Described herein are liquid formulations which deliver a variety of therapeutic agents, including but not limited to rapamycin, to a subject for an extended period of time； liquid formulations which form a non-dispersed mass when placed in an aqueous medium of a subject； liquid formulations comprising a therapeutic agent and a plurality of polymers； and methods for delivering therapeutic agents to a subject for an extended period of time using the liquid formulations. The liquid formulation may be placed in an aqueous medium of a subject, including but not limited to via intraocular or periocular administration. A method may be used to administer rapamycin to treat or prevent angiogenesis, choroidal neovascularization, or age-related macular degeneration in a subject.
