Sreenivasu MUDUMBA,Philippe JM DOR,Thierry NIVAGGIOLI,David A. WEBER,Sidiq FAROOQ
申请号:
US15806226
公开号:
US20180311152A1
申请日:
2017.11.07
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Described herein are liquid formulations which deliver a variety of therapeutic agents, including but not limited to rapamycin, to a subject for an extended period of time; liquid formulations which form a non-dispersed mass when placed in an aqueous medium of a subject; liquid formulations comprising a therapeutic agent and a plurality of polymers; and methods for delivering therapeutic agents to a subject for an extended period of time using the liquid formulations. The liquid formulation may be placed in an aqueous medium of a subject, including but not limited to via intraocular or periocular administration. A method may be used to administer rapamycin to treat or prevent angiogenesis, choroidal neovascularization, or age-related macular degeneration in a subject.