antigen peptide or functional fragment thereof, pharmaceutical composition, methods for treating a neurodegenerative disease or disorder such as tauopathy, to induce an immune response in an animal, to diagnose a disease, disorder or condition and a predisposition to disease, disorder or condition, to monitor minimal residual disease in a patient and to predict a patient's receptivity, antibody, test kit, epitope, and cell line.
AC IMMUNE S.A. E K. U. LEUVEN RESSEARCH & DEVELOPMENT
发明人:
ANDREA PFEIFER,ANDREAS MUHS,FRED VAN LEUVEN,MARIA PIHLGREN
申请号：
BRPI1015088
公开号：
BRPI1015088A2
申请日:
2010.04.01
申请国别(地区):
BR
年份:
2016
代理人:
摘要：
The present invention is related to methods and pharmaceutical compositions for the therapeutic and diagnostic use in the treatment of diseases and disorders which are caused by or associated with neurofibrillary tangles. In particular, the invention relates to pharmaceutical composition comprising an antigenic peptide, particularly an antigenic phospho-peptide mimicking a major pathological phospho-epitope of protein tau, for the therapeutic and diagnostic use in the treatment of tauopathies including Alzheimer's Disease.
