CENTRE HOSPITALIER UNIVERSITAIRE DE NANTES;UNIVERSITE DE NANTES;INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)
发明人:
Carole GUILLONNEAU,Ignacio ANEGON,Severine BEZIE
申请号：
US15740997
公开号：
US20180187151A1
申请日:
2016.07.01
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Disclosed is a method for obtaining a population of human Treg cells including the steps of: (a) culturing a population of human monocytes with a medium including an amount of an interleukin-34 (IL-34) polypeptide in order to obtain a population of immunosuppressive macrophages； (b) co-culturing a population of human peripheral blood mononuclear cells (PBMCs) and the population of immunosuppressive macrophages obtained at step (a).
