INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE);UNIVERSITE DE NANTES;CENTRE HOSPITALIER UNIVERSITAIRE DE NANTES
发明人:
Carole GUILLONNEAU,Ignacio ANEGON,Severine BEZIE
申请号：
US16899142
公开号：
US20200308543A1
申请日:
2020.06.11
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Disclosed is a method for obtaining a population of human Treg cells including the steps of: (a) culturing a population of human monocytes with a medium including an amount of an interleukin-34 (IL-34) polypeptide in order to obtain a population of immunosuppressive macrophages； (b) co-culturing a population of human peripheral blood mononuclear cells (PBMCs) and the population of immunosuppressive macrophages obtained at step (a).
