The purpose of the present invention is to provide: a composition for effectively inducing apoptosis and/or proliferation inhibition in cells and a method in which the composition is used. The present invention relates to: an agent for inducing apoptosis, which contains a GST-π-inhibiting drug and a RB1CC1-inhibiting drug as active ingredients a pharmaceutical composition which contains the agent a method for treating a disease associated with an abnormality in apoptosis, in which the agent is used and others.