In accordance with at least one exemplary embodiment, a syringe device, method and system for delivering a therapeutic amount of ozone are disclosed. A sterility case can enclose a syringe portion and can maintain sterility while the syringe device is interfaced to an ozone generator. A valvably-controlled fluid channel can extend from the barrel of the syringe through the case. Conducting elements can be attached to the case and can breach the case. The conductive elements can be connected to electrodes. The electrodes can be attached to the syringe. The syringe portion can be filled with oxygen gas via the valvably-controlled fluid channel. An electric current can be provided to the conductive elements from an ozone generator resulting in a corona discharge from at least one electrode. A therapeutic amount of ozone gas can be produced from the oxygen gas and the syringe delivered into the sterile field without compromise.