TAKKINEN, KRISTIINA,LAUKKANEN, MARJA-LEENA,SÖDERLUND, HANS,JYLHÄ, SIRPA,HOLKERI, HEIDI,NIEMI, MERJA,JÄNIS, JANNE,ROUVINEN, JUHA
申请号:
PL12714328
公开号:
PL2699681T3
申请日:
2012.04.18
申请国别(地区):
PL
年份:
2019
代理人:
摘要:
The present invention provides mutant polypeptides useful as hypoallergens. More specifically the present invention provides mutant Bet v 1 proteins and the use of such polypeptides as hypoallergens for desensitizing against birch pollen allergies. Furthermore, the invention provides vaccine formulations comprising such polypeptides; the use of such formulations; and to methods of vaccination against birch pollen allergy.