TAKKINEN, Kristiina,LAUKKANEN, Marja-Leena,SOEDERLUND, Hans,JYLHÄ, Sirpa,HOLKERI, Heidi,NIEMI, Merja,JÄNIS, Janne,ROUVINEN, Juha
申请号:
HUE12714328
公开号:
HUE038998T2
申请日:
2012.04.18
申请国别(地区):
HU
年份:
2018
代理人:
摘要:
The present invention provides mutant polypeptides useful as hypoallergens. More specifically the present invention provides mutant Bet v 1 proteins and the use of such polypeptides as hypoallergens for desensitizing against birch pollen allergies. Furthermore, the invention provides vaccine formulations comprising such polypeptides; the use of such formulations; and to methods of vaccination against birch pollen allergy.