Described herein are topical formulations for use in the treatment or prevention of dermatological diseases, disorders, or conditions in a mammal. Topical formulations disclosed herein include a DP2receptor antagonist compound formulated for dermal administration.本文描述用於治療或預防哺乳動物之皮膚疾病、病症或病況之表面局部用調配物。本文揭示之表面局部用調配物包括針對皮膚投與所調配之DP2受體拮抗劑化合物。