GREEN Luke,GUBA Wolfgang,JAESCHKE Georg,JOLIDON Synese,LINDEMANN Lothar,RICCI Antonio,RUEHER Daniel,STADLER Heinz,VIEIRA Eric
申请号:
SI201130777
公开号:
SI2558457T1
申请日:
2011.04.11
申请国别(地区):
SI
年份:
2016
代理人:
摘要:
The present invention relates to ethynyl compounds of formula I wherein R1, R2, R2′, R3, R3′, R4, R4′, U, V, W, Y, m, and n are as defined herein and to a pharmaceutically acceptable acid addition salts, to a racemic mixtures, or to its corresponding enantiomers and/or optical isomers and/or stereoisomers thereof. Compounds of formula I are allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5).