Green, Luke,Guba, Wolfgang,Jaeschke, Georg,Jolidon, Synese,Lindemann, Lothar,Ricci, Antonio,Rueher, Daniel,Stadler, Heinz,Vieira, Eric
申请号：
HRP20160617
公开号：
HRP20160617T1
申请日:
2016.06.07
申请国别(地区):
HR
年份:
2016
代理人:
摘要：
The present invention relates to ethynyl compounds of formula I wherein R1, R2, R2&prime；, R3, R3&prime；, R4, R4&prime；, U, V, W, Y, m, and n are as defined herein and to a pharmaceutically acceptable acid addition salts, to a racemic mixtures, or to its corresponding enantiomers and/or optical isomers and/or stereoisomers thereof. Compounds of formula I are allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5).
