George Shlieout,Bernd Boedecker,Siegfried Schaefer,Bernd Thumbeck,Peter-Colin Gregory
申请号：
US14308543
公开号：
US20140302000A1
申请日:
2014.06.18
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Orally administrable pharmaceutical compositions of lipase-containing products, particularly pancreatin and pancreatin-containing products, or of enzyme products which contain at least one lipase of non-animal, especially microbial origin, which improve the lipolytic activity and particularly result in stabilization of the lipase in the acidic pH range. These oral pharmaceutical compositions contain a system which includes at least one surfactant and one co-surfactant and optionally a lipophilic phase, and are self-emulsifiable on contact with a hydrophilic and a lipophilic phase. The compositions according to the invention are suitable for treating or inhibiting maldigestion, especially maldigestion due to chronic exocrine pancreatic insufficiency, in mammals and humans.
