Ryan M. MOSLIN,David S. WEINSTEIN,Stephen T. WROBLESKI,Yanlei ZHANG,John S. TOKARSKI,Michael E. MERTZMAN,Chunjian LIU
申请号：
HK16114678.2
公开号：
HK1226400A
申请日:
2016.12.23
申请国别(地区):
HK
年份:
2017
代理人:
摘要：
Compounds having the following formula I:or a stereoisomer or a pharmaceutically-acceptable salt thereof, wherein R<；sup>；1<；/sup>；, R<；sup>；2<；/sup>；, R<；sup>；3<；/sup>；, R<；sup>；4<；/sup>；, and R<；sup>；5<；/sup>；are as defined herein, are useful in the modulation of IL-12, IL-23 and/or IFNα by acting on Tyk-2 to cause signal transduction inhibition.
