A method for selection of surgical approach algorithm at acute pancreatitis involves patient status investigation by Ranson score and APACHE II score, assessment of indices in scores and determination of blood plasma index. Additionally determined are a procalcitonin (PCT) level, transforming growth factor(1 in blood serum, and SCT is performed with determination of Balthazar CT-index. If Balthazar CT-index is within from 4 to 6 scores and PCT concentration value is less than 2 ng/ml, TGF- (1 <; 80.0 ng/ml, first treatment mode is used (draining the accumulated fluid under US control), if at the same values of Balthazar CT-index the PCT concentration is more than or equal to 2 ng/ml, and TGF-(1 ( 80.0 <; 120.0 ng/ml, first and/or second treatment mode is used. When Balthazar CT-index is within from 7 to 10 scores, TGF-(1 is within (120.0 <; 150.0 ng/ml and PCT takes the value less than 2 ng/ml at first stage first and/or second treatment mode is performed, if Balthazar CT-index is 7-10 scores and TGF-(1 level is more than 150.0 ng/ml, PCT concentration exceeds 2 ng/ml, third treatment mode is performed. Positive effect of treatment is estimated by reducing values of APACHE II scale, if after first stage of surgical treatment for next days of observation value of APACHE II scale is increased by 4 scores the control SCT is performed, levels of TGF-(1, PCT and NSI are determined, and if Balthazar CT-index value is increased by 2-3 scores, second stage of surgical treatment is performed, wherein first or third treatment mode is used.Способ выбора алгоритма хирургической тактики при остром панкреатите включает исследование состояния по шкале Ranson и шкале APACHE II, оценку показателей в баллах и определение показателя плазмы крови. Также дополнительно определяют уровень прокальцитонина (ПКТ), уровень трансформирующего фактора роста (1 в сыворотке крови и выполняют СКТ и определяют КТ - индекс Balthazar, в случаях, когда КТ - индекс Balthazar находится в пределах о