The present Invention Bertalanffy refers to compounds of the General formula F & amp； (i), wherein R1 is Hydrogen & amp； geno, Geno, Hal & amp； alkyl alkoxy Lower, Lower, Lower alkoxy substituted by Hal & amp； geno or cyano； R2 is Hydrogen & acute； Hydrogen, alkyl or alkyl substituted Lower Lower Hal & acute； R3 is phenyl, benzo [1,3] dioxolilo, 2,3 - dihydro - benzofuran - 5 - ilo or a heteroaryl 5 & amp； 6 links, such groups and heteroaryl phenyl 5 & amp； 6 Links can be replaced by one or M & aacute； S substituents selected from cyano, Nitro, amino, and di (Lower alkyl) amino -, (Lower alkyl) - sulfonyl, Lower alkoxy IOR, Lower alkoxy substituted by Hal & amp； geno, Geno, Hal & amp； Lower alkyl,Lower alkyl substituted by Hal & amp； Hydrogen or lower alkyl substituted by hydroxyl； X is - ch (Lower alkyl) -, - CH2 -, - or - ch2ch2 CH2 CH (Lower alkyl) -； R is Hydrogen or lower alkyl GENO & amp； n； n is the Number 1 Brand & acute；； 2； or an addition Salt of Bertalanffy & aacute； acid Pharmaceutical & eac Ute uticamente acceptable；A mixture RAC & eacute； mica or enanti & acute； grouper and / or is & amp； mere & amp； Optical.The compounds can be used for the treatment of schizophrenia, obsessive-compulsive Personality Disorder, depression Bertalanffy, bipolar disorder, Anxiety Disorders, normal Aging, Epilepsy, degeneraci Bertalanffy retinal injury & acute； No Brain Traum & aacute； tica, Lesi Bertalanffy of SpineThe disorder of estr & eacute； s Post Traum & aacute； tico, the disorder of P & aacute； nico, Parkinson's disease, dementia, Alzheimer's disease, mild cognitive imbalance, Cognitive dysfunction Bertalanffy induced by chemotherapy, the S & amp； Down Syndrome； disorders of ESP Ectro autistic, P & eacute； Hearing Loss, noise, spinocerebellar ataxia,Amyotrophic lateral sclerosis amiotr fica, & acute； M & Multiple Sclerosis', Huntington's disease, stroke & iacute； a, Radiation Therapy, Stress & eacute； S CR & amp； nico Neuroactive Drugs, the abuse of alcohol, for e
