The present invention is directed to a replacement valve for use within a human body comprising a valve component, a stent component for housing the valve component, an inner skirt covering at least a portion of an outer surface of the valve component and an outer skirt covering an outer surface of the stent component. The topology of the inner surface of the inner skirt is configured to improve blood flow and the topology of the outer surface of the outer skirt is configured to improve endothelialization.