Modulation of diacylglycerol acyltransferase 1 expression

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专利权人:

Brett P. Monia

发明人:

Brett P. Monia,Mark J. Graham

申请号：

US12173744

公开号：

US08158597B2

申请日:

2008.07.15

申请国别(地区):

US

年份:

2012

代理人:

摘要：

Compounds, compositions and methods are provided for modulating the expression of diacylglycerol acyltransferase 1. The compositions comprise oligonucleotides, targeted to nucleic acid encoding diacylglycerol acyltransferase 1. Methods of using these compounds for modulation of diacylglycerol acyltransferase 1 expression and for diagnosis and treatment of disease associated with expression of diacylglycerol acyltransferase 1, such as obesity and obesity-related conditions, are provided.

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