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Compositions and methods for stabilizing lipid based adjuvant formulations using glycolipids
专利权人:
Ida Rosenkrands;Peter Andersen;Jesper Davidsen
发明人:
Jesper Davidsen,Peter Andersen,Ida Rosenkrands
申请号:
US12784821
公开号:
US08277823B2
申请日:
2010.05.21
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to liposome formulations that are physically stable. In particular the present invention relates to steric stabilization of cationic liposomes by incorporating glycolipids into the liposomes. The stabilized liposomes can be used either as an adjuvant for antigenic components or as a drug delivery system. In particular the invention relates to vaccines with adjuvants in aqueous media for immunization, where the final product is stable.
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