The present invention relates to liposome formulations that are physicallystable. In particular the present invention relates to steric stabilization ofcationic liposomes by incorporating glycolipids into the liposomes. Thestabilized liposomes can be used either as an adjuvant for antigeniccomponents or as a drug delivery system. In particular the invention relatesto vaccines with adjuvants in aqueous media for immunization, where the finalproduct is stable.