Substances and methods useful for influencing tumor cell growth, migration and invasion

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专利权人:

ジ・オハイオ・ステート・ユニバーシティ

发明人:

クローチェ，カルロ・エム,クローチェ,カルロ・エム

申请号：

JP2012541156

公开号：

JP5960060B2

申请日:

2010.11.23

申请国别(地区):

JP

年份:

2016

代理人:

摘要：

It is disclosed herein that miR-221 and miR-222 down-regulate PTEN and TIMP3 tumor suppressors, resulting in TRAIL resistance. The present invention provides research, diagnostic, and therapeutic tools and methods related to this discovery. Diagnostics, prognostics and treatments for human hepatocellular cancer and non-small cell lung carcinoma having a TRAIL resistance are particularly described herein.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/