CENTRO SUPERIOR DE INVESTIGACION EN SALUD PUBLICA (CSISP)
发明人:
MIRA OBRADOR, ALEJANDRO
申请号:
CA2808793
公开号:
CA2808793A1
申请日:
2011.08.31
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The present invention relates to various specific bacterial strains isolated from individuals without caries, and characterized in that the strains have an inhibitory activity against cariogenic organisms. The invention also relates to a method for isolating said strains, as well as bioactive peptides, i.e. antimicrobial peptides of human and bacterial origin which also exhibit anticaries activity. The invention additionally relates to pharmaceutical compositions and/or probiotics/prebiotics, functional foods, mouthwashes, toothpaste, chewing gum, etc. that include at least one of the strains and/or at least one of the bioactive peptides of the invention or a combination thereof, and which are useful in the treatment and/or prevention of infectious diseases of the oral cavity, preferably caries.