INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE);PHARMA CYTUNE
发明人:
SÉBASTIEN DANIEL MORISSEAU,GÉRALDINE TEPPAZ,YANNICK LAURENT JOSEPH JACQUES,BRUNO, GILBERT MARC ROBERT,GUY LUC MICHEL DE MARTYNOFF,DAVID BECHARD
申请号:
PT12731303
公开号:
PT2723869T
申请日:
2012.06.22
申请国别(地区):
PT
年份:
2019
代理人:
摘要:
The present invention relates to an immunocytokine comprising (a) a conjugate, and (b) an antibody or a fragment thereof directly or indirectly linked by covalence to said conjugate, wherein said conjugate comprises (i) a polypeptide comprising the amino acid sequence of the interleukin 15 or derivatives thereof, and a polypeptide comprising the amino acid sequence of the sushi domain of the IL-15R± or derivatives thereof; and uses thereof.