CYTUNE PHARMA;INSERM (Institut National de la Sante et de la Recherche Medicale)
发明人:
MORISSEAU, Sebastien Daniel,TEPPAZ, Geraldine,JACQUES, Yannick,ROBERT, Bruno,DE MARTYNOFF, Guy,BECHARD, David
申请号:
HUE12731303
公开号:
HUE043442T2
申请日:
2012.06.22
申请国别(地区):
HU
年份:
2019
代理人:
摘要:
The present invention relates to an immunocytokine comprising (a) a conjugate, and (b) an antibody or a fragment thereof directly or indirectly linked by covalence to said conjugate, wherein said conjugate comprises (i) a polypeptide comprising the amino acid sequence of the interleukin 15 or derivatives thereof, and a polypeptide comprising the amino acid sequence of the sushi domain of the IL-15R± or derivatives thereof; and uses thereof.