Sara Bonacchi,Marco Montalti,Luca Prodi,Nelsi Zaccheroni,Riccardo Juris,Damiano Genovese,Enrico Rampazzo
申请号：
US13879408
公开号：
US20130315835A1
申请日:
2011.10.13
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention relates to silica nanoparticles comprising at least two dyes. Said dyes have a respective relationship of donor-acceptor couple in an energy transfer process and have a molar absorption coefficient ≧10,000 M−1 cm−1 for the considered spectral region, a fluorescence quantum yield ≧0.01, good overlap integral, according to the Förster theory, between said donor and said acceptor dye said active compounds may be lipophilic or may present a functionality useful for the introduction of a trialkoxysilane moiety. The dyes provide an efficient energy transfer process. Said nanoparticles are useful as probes in the field of medicine, in particular therapy and diagnostics, more particularly in theranostics, and in the field of analytical chemistry.
