Oligonucleotide variants containing modified nucleic acids and guanosine with therapeutic efficacy

• 收藏
• 分享

专利权人:

アプタバイオ セラピュティックス インコーポレイテッド

发明人:

リー スー ジン,ムーン スン フワン

申请号：

JP2012518491

公开号：

JP5841938B2

申请日:

2010.06.29

申请国别(地区):

JP

年份:

2016

代理人:

摘要：

The present invention relates to a novel modified oligonucleotide comprising at least one guanosine molecule and a modified nucleic acid with therapeutic efficacies. The present invention also relates to a pharmaceutical composition having cell apoptotic activity against cancer cells for preventing or treating cancer comprising a guanosine-rich modified oligonucleotide with at least one therapeutically effective modified nucleic acid (N), or its pharmaceutically acceptable salt as active ingredient.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/