PHARMACEUTICAL COMPOSITION CONTAINING 8 OXO-DEOXYGUANOSINE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AS ACTIVE INGREDIENT FOR TREATING CORNEAL DISEASE
GACHON UNIVERSITY OF INDUSTRY-ACADEMIC COOPERATION FOUNDATION;GIL MEDICAL CENTER
发明人:
Myung-Hee Chung,Dong Hyun Kim
申请号：
US16376140
公开号：
US20190282596A1
申请日:
2019.04.05
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention relates to a pharmaceutical composition for treating corneal disease containing 8-oxo-deoxyguanosine (8-oxo-2′；-deoxyguanosine) or a pharmaceutically acceptable salt thereof as an active ingredient. Specifically, by confirming that a corneal epithelium was restored (regenerated) quicker and the clarity of a cornea improved when it was administered to a mouse model of corneal disease induced by ethanol, 8-oxo-deoxyguanosine (8 -oxo-2′；-deoxyguanosine) of the present invention may be useful for the treatment of corneal disease.
