LIU, QINGJIE,BATT, DOUGLAS G,DELUCCA, GEORGE V,SHI, QING,TEBBEN, ANDREW J
申请号:
NZ59309609
公开号:
NZ593096A
申请日:
2009.12.17
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed herein are fused carbazole carboxamide compounds of formula (I), wherein the substituents are as defined within the specification; processes for their preparation, compositions comprising said compounds and uses thereof. Said compounds are useful as kinase inhibitors, including the modulation of Bruton's tyrosine kinase (Btk) and other Tec family kinases such as Itk, as such said compounds/compositions are useful in the treatment of systemic lupus erythematosus (SLE), rheumatoid arthritis, multiple sclerosis (MS), or transplant rejection.