TASKEN, KJETIL,LYGREN, BIRGITTE,ØSTENSEN, ELLEN,KLAVENESS, JO
申请号：
PL13723783
公开号：
PL2861568T3
申请日:
2013.05.17
申请国别(地区):
PL
年份:
2019
代理人:
摘要：
The present invention relates to tertiary amines of formula (I) for use in therapy, particularly for use in treating cardiovascular disorders. The compounds have been found to regulate phospholamban phosphorylation by interfering with the A-kinase anchor protein 18delta (AKAP185) binding to the PKA substrate phospholamban. The compounds share a tri(alkylaryl/alkylheteroaryl)amine structure.
