The present invention relates to the use of an antisecretory protein, derivative, homologue,and/or fragment thereof, having equivalent activity, and/or a pharmaceutically activesalt thereof, for the manufacture of a pharmaceutical composition and/or a medicalfood for the treatment and/or prevention of dysfunction, e.g. abnormal function,hypo-orhyper-function of lipid rafts, receptors and/or caveolae. A dysfunctionof lipid rafts, receptors and/or caveolae may be caused by or be a cause of a varietyof other conditions, which are also encompassed by the present invention, suchas vascular, and lung dysfunctions, and/or endocrine disorders, e.g. diabetesand related disorders. Furthermore, the invention relates to a method for thetreatment and/or prevention of dysfunction of lipid rafts and/or caveolae ina mammal in need thereof.
