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Tolvaptan solid dispersion and its preparation method
专利权人:
JIANGSU HENGRUI MEDICINE CO.; LTD.
发明人:
WU, YU-XIA,MAO, SHU-JUN,CHEN, HAO
申请号:
TW100131876
公开号:
TW201249802A
申请日:
2011.09.05
申请国别(地区):
TW
年份:
2012
代理人:
摘要:
The present invention relates to a tolvaptan solid dispersion and its preparation method, particularly a solid dispersion comprising tolvaptan and a carrier crosslinked polyvinylpyrrolidone, the solid dispersion preferably further comprises water-soluble polymers, wherein said solid dispersion exhibits better thermodynamic stability and solubility, the pharmaceutical composition comprising said tolvaptan solid dispersion of the present invention can improve the release rate and bioavailability.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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