JARRETT, PETER,EL-HAYEK, RAMI,SAWHNEY, AMARPREET S.
申请号:
CA2969716
公开号:
CA2969716A1
申请日:
2015.12.10
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
Materials and methods for treating a patient, optionally a patient with an eye disease, comprising providing a collection of particles that comprise a first biodegradable material that is a hydrogel or a xerogel and a therapeutic agent, with the first material, before biodegradation, having a rate of release for the therapeutic agent as measured in physiological solution, and forming a second hydrogel ex vivo or in situ on a tissue of the patient at a site of intended use, optionally at or near an eye, that at least partially coats the collection of particles. The agent is released to treat the patient.