Zhou, Heyue,Gastwirt, Randy,Swanson, Barbara A.,Gray, John Dixon,Kaufmann, Gunnar F.
申请号:
AU2020204113
公开号:
AU2020204113A1
申请日:
2020.06.19
申请国别(地区):
AU
年份:
2020
代理人:
摘要:
#$%^&*AU2020204113A120200709.pdf#####Abstract There is disclosed compositions and methods relating to or derived from anti-PD-Li antibodies. More specifically, there is disclosed fully human antibodies that bind PD-Li, PD-Li-binding fragments and derivatives of such antibodies, and PD-Li -binding 5 polypeptides comprising such fragments. Further still, there is disclosed nucleic acids encoding such antibodies, antibody fragments and derivatives and polypeptides, cells comprising such polynucleotides, methods of making such antibodies, antibody fragments and derivatives and polypeptides, and methods of using such antibodies, antibody fragments and derivatives and polypeptides, including methods of treating or diagnosing subjects 10 having PD-Li related disorders or conditions, including various inflammatory disorders and various cancers.