Anti-PD-L1 antibodies and uses thereof

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专利权人:

I-Mab Biopharma US Limited

发明人:

Fang, Lei,Wang, Zhengyi,Guo, Bingshi,Zang, Jingwu

申请号：

AU2020217358

公开号：

AU2020217358A1

申请日:

2020.08.11

申请国别(地区):

AU

年份:

2020

代理人:

摘要：

#$%^&*AU2020217358A120200903.pdf#####1003108248 ABSTRACT Provided are anti-PD-Li antibodies or fragments thereof The antibodies or fragments thereof specifically bind to the immunoglobulin C domain of the PD-Li protein. In various example, the antibodies or fragments thereof include a VH CDRi of SEQ ID NO: 1, a VH CDR2 of SEQ ID NO: 2, a VH CDR3 of SEQ ID NO: 3, a VL CDRi of SEQ ID NO: 4, a VL CDR2 of SEQ ID NO: 5, and a VL CDR3 of SEQ ID NO: 6, or variants of each thereof. Methods of using the antibodies or fragments thereof for treating and diagnosing diseases such as cancer and infectious diseases are also provided. -77-

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