Human anti-PD-1, PD-L1, and PD-L2 antibodies and uses therefor

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专利权人:

DANA-FARBER CANCER INSTITUTE; INC.

发明人:

FREEMAN, Gordon J.,AHMED, Rafi,JONES, Timothy D.,CARR, Francis J.,GREGSON, James P.

申请号：

AU2013204875

公开号：

AU2013204875B2

申请日:

2013.04.12

申请国别(地区):

AU

年份:

2016

代理人:

摘要：

#$%^&*AU2013204875B220160512.pdf#####Abstract The present invention is based, in part, on the identification of novel human anti-PD-1, PD-Li, and PD-L2 antibodies. Accordingly, the invention relates to compositions and methods for diagnosing, prognosing, and treating conditions that would benefit from modulating PD-1, PD-LI, and/or PD-L2 activity (e.g., persistent infectious diseases, autoimmune diseases, asthma, transplant rejection, inflammatory disorders and tumors) using the novel human anti-PD-1, PDL 1, and PD-L2 antibodies described herein. 4255491_1 (GHMatters) P86720.AU.2

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http://www.ckcest.cn/home/