COMPOSITIONS AND METHODS FOR TRANSIENT IMMUNE RESPONSE MODULATION DURING VACCINATION

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专利权人:

发明人:

申请号：

EP15845450.4

公开号：

EP3197558A1

申请日:

2015.09.28

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

In certain aspects the invention provides a selection of HIV-1 envelopes suitable for use as immunogens, and methods of using these immunogens to induce neutralizing antibodies. In certain embodiments, the immunogens are designed to trimerize. In other embodiments, the immunogenic compositions and methods comprise at least one agent for transient immune response modulation during vaccination.

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