Barton F. HAYNES,Garnett KELSOE,Masayuki KURAOKA,M. Anthony MOODY,Hua-Xin LIAO,Laurent VERKOCZY
申请号：
US15514789
公开号：
US20170216426A1
申请日:
2015.09.28
申请国别(地区):
US
年份:
2017
代理人:
摘要：
In certain aspects the invention provides a selection of HIV-1 envelopes suitable for use as immunogens, and methods of using these immunogens to induce neutralizing antibodies. In certain embodiments, the immunogens are designed to trimerize. In other embodiments, the immunogenic compositions and methods comprise at least one agent for transient immune response modulation during vaccination.
