AHMED KARIEM,EL ANDALOUSSI SAMIR,GUTERSTAM PETER,HÄLLBRINK MATTIAS,JOHANSSON HENRIK,LANGEL ÜLO,LEHTO TAAVI,LINDGREN MARIA,MÄGER IMRE,SILLARD RANNER,ROSENTHAL AIZMAN, KATRI,TEDEBARK ULF,LUNDIN PER
申请号:
EP09818057
公开号:
EP2355852A4
申请日:
2009.09.16
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
The present invention relates to a system for intracellular delivery of a cargo comprising at least one component A chosen from aliphatic linear or branched moieties with at least 4 carbon atoms and/or cyclic ring systems comprising 2-4 rings which may contain several hetero atoms chosen from N, S, O and P, wherein component(s) A is (are) attached to a cell penetrating peptide B and/or a non-peptide analogue thereof. It also relates to methods of using the system in diagnosis of diseases, as research tool and as a targeting system, a composition comprising the system and especially a pharmaceutical composition a material covered with the system and a material having the delivery systems into the material. Finally it relates to novel peptides.