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1,2,4-oxadiazole benzoic acid compounds and their use for nonsense suppression and the treatment of disease
专利权人:
PTC THERAPEUTICS INC
发明人:
KARP GARY MITCHELL,HWANG SEONGWOO,CHEN GUANGMING,ALMSTEAD NEIL GREGORY,MOON YOUNG-CHOON
申请号:
NO20055314
公开号:
NO332843B1
申请日:
2005.11.10
申请国别(地区):
NO
年份:
2013
代理人:
摘要:
The present invention relates to a compound 3-[5-(2-Fluoro-phenyl)-[1,2,4]oxadiazol-3-yl]-benzoic acid, having the structure: or a pharmaceutically acceptable salt thereof. The present invention also relates to a pharmaceutical composition and a single unit dosage thereof, as well as the said compound for use in a method of treating, preventing or ameliorating diseases as defined herein.Nye 1,2,4-oksadiazolbenzosyreforbindelser, fremgangsmåter for anvendelse og farmasøytiske sanmiensetninger som irmbefatter et 1,2,4-oksadiazolbenzosyrederivat er beskrevet. Fremgangsmåtene inkluderer fremgangsmåter for behandling eller hindring av en sykdom som lindres ved modulering av prematur franslasjonsterminering eller nonsensmediert mRNA-reduksjon, eller som lindrer et eller flere symptomer assosiert dermed.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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