SLOAN KETTERING INSTITUTE FOR CANCER Memorial Sloan Kettering Cancer Center
发明人:
Jimmy Andrew Rotolo,Richard N. Kolesnick
申请号:
US14402875
公开号:
US20150216971A1
申请日:
2013.05.29
申请国别(地区):
US
年份:
2015
代理人:
摘要:
It has been discovered that administering therapeutically effective amounts of an antibiotic that kills Gram-negative bacteria, together with an anti-ceramide antibody or anti-ceramide mimetic, treats and prevents an array of diseases mediated by cytolytic T lymphocyte (CTL)-induced killing and/or by damage to endothelial microvasculature, including Radiation GI syndrome, CGvHD disease, inflammatory diseases and autoimmune diseases.