< Topic >Being the blood purifier which possesses the high permeability efficiency which is used for the remedy of chronic kidney incompletion, the efficiency in remedying it offers the blood purifier which features that it does not fluctuate with the state of the patient.SolutionsAs for this invention, average film thickness 50 millimicron or less of 10 millimicrons or more, being the hollow yarn membrane where average pore radius is 300 or less of 150 or more, water permeability of pure water in the 37C below 1500mL/m2/hr/mmHg above 150mL/m2/hr/mmHg, is the hollow yarn membrane which is superior in the efficiency stability which features that ratio (Ko2 /Komyo) of general mass transfer coefficient (Komyo) of the myoglobin aqueous solution and general mass transfer coefficient (Ko2) of the blood plasma solution of the 2-mikuro globulin is the 1.0 or less of 0.7 or more.< Selective figure >It is not【課題】慢性腎不全の治療に用いる高透水性能を有する血液浄化器であって、治療における性能が患者の状態によって変動しないことを特徴とする血液浄化器を提供する。【解決手段】本発明は、平均膜厚が10μm以上50μm以下、平均細孔半径が150Å以上300Å以下である中空糸膜であって、37℃における純水の透水性が150mL/m2/hr/mmHg以上1500mL/m2/hr/mmHg以下、ミオグロビン水溶液の総括物質移動係数(Komyo)とβ2-ミクログロブリンの血漿溶液の総括物質移動係数(Koβ2)の比(Koβ2/Komyo)が0.7以上1.0以下であることを特徴とする性能安定性に優れた中空糸膜である。【選択図】なし