MADIHA SABIHA DEROUAZI;Paul R. Walker;Pierre-Yves Dietrich
发明人:
MADIHA SABIHA DEROUAZI,Paul R. Walker,Pierre-Yves Dietrich
申请号：
US13415877
公开号：
US20120231030A1
申请日:
2012.03.09
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention relates to isolated polypeptides comprising: (i) a protein transduction domain consisting of ZEBRA or a fragment thereof that retains the capacity of internalization, (ii) at least one CD4+ epitope； and (iii) at least one CD8+ epitope. It also relates to antigen presenting cells loaded with said polypeptides, and the use thereof in immunotherapy including prevention and/or treatment of cancers or infectious diseases.
