Dashper, Stuart Geoffrey,Reynolds, Eric Charles,Veith, Paul David,Ang, Ching Seng
申请号：
AU2007264402
公开号：
AU2007264402B2
申请日:
2007.06.27
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
The invention is directed to vaccine compositions and methods based on proteins identified to be regulated by haem availability that can be used in the prevention and treatment of periodontal disease. In particular, two specific internalin-like P. gingivalis proteins, namely PG0350 and PG1374 involved in the internalization of by host cells, the hypothetical protein, PG1019 purported to be a cell surface lipoprotein and the alkyl hydroperoxide reductase protein, PG0618 have been identified as useful targets for the prevention and treatment of periodontal disease.
