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Crystalline form of a pleuromutiline
专利权人:
Nabriva Therapeutics AG
发明人:
Riedl, Rosemarie,Heilmayer, Werner,SPENCE, Lee
申请号:
DK11724938
公开号:
DK2576505T3
申请日:
2011.05.23
申请国别(地区):
DK
年份:
2018
代理人:
摘要:
A process for the preparation of a compound of formula in the form of a single stereoisomer, comprising deprotecting the amine group in an N-protected amino-hydroxy-cyclohexylsulfanyl-acetyl-mutilin of formula wherein R is an amine protecting group in the form of a single stereoisomer, and isolating a compound of formula I in the form of a single stereoisomer obtained from the reaction mixture; compounds obtainable by such processes, e.g. a compound of formula I in a crystalline form, or salts of a compound of formula I in crystalline form, and processes for the preparation of intermediates for the production of a compound of formula I.
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