ZHANG YANSHENG,TEOH THOMAS KEAT,REED DARWIN W.,OLSON DOUGLAS J.H.,ROSS ANDREW R. S.,COVELLO PATRICK S.
申请号：
US20080734791
公开号：
US2010299778(A1)
申请日:
2008.11.19
申请国别(地区):
美国
年份:
2010
代理人:
摘要：
An isolated nucleic acid molecule cloned from Artemisia annua encodes an artemisinic aldehyde double bond reductase. Artemisinic aldehyde double bond reductase enzymatically reduces artemisinic aldehyde to (11R)-dihydroartemisinic aldehyde. The nucleic acid molecule, and the enzyme encoded thereby, may be used in processes to produce dihydroartemsinic aldehyde and/or dihydroartemisinic acid in a host cell. Dihydroartemisinic acid is a late precursor to the antimalarial compound artemisinin.
