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ВАКЦИННЫЙ АНТИГЕН БАБЕЗИОЗА СОБАК
专利权人:
ИНТЕРВЕТ ИНТЕРНЭШНЛ Б.В. (NL)
发明人:
СХЕТТЕРС Теодорус Петрус Мария (NL),МУБРИ-МЕНАЖ Карина (FR),КЛЕСКЕНС Йос (NL),РОВЕР Андреас (DE)
申请号:
RU2013135002/10
公开号:
RU2013135002A
申请日:
2011.12.28
申请国别(地区):
RU
年份:
2015
代理人:
摘要:
1. An isolated polypeptide comprising an amino acid sequence having amino acid sequence identity of more than 53% with the amino acid sequence of SEQ ID NO: 1, and / or having amino acid sequence identity more than 58% with the amino acid sequence of SEQ ID NO: 3, wherein said polypeptide is capable of inducing an immune response against the parasite Babesia sobak.2. The polypeptide of claim 1 having the amino acid sequence identity of more than 29% of at least one amino acid sequence selected from the group consisting of SEQ ID NO: 6, SEQ ID NO: 7 and SEQ ID NO: 8 or an immunogenic fragment of said polypeptide .3. An isolated nucleotide sequence capable of encoding a polypeptide or an immunogenic fragment thereof according to claim 1 or 2.4. The nucleotide sequence of claim 3 having a nucleotide sequence identity of more than 70% of at least one nucleotide sequence selected from the group consisting of SEQ ID NO: 9, SEQ ID NO: 10, SEQ ID NO: 11, SEQ ID NO: 12, SEQ ID NO: 13 and SEQ ID NO: 14.5. The nucleotide sequence of claim 3 or 4, which can hybridize under stringent conditions with at least one nucleotide sequence selected from the group consisting of SEQ ID NO: 9, SEQ ID NO: 10, SEQ ID NO: 11, SEQ ID NO : 12, SEQ ID NO: 13 and SEQ ID NO: 14.6. An isolated nucleic acid comprising a nucleotide sequence according to any of claims 3-5, wherein said nucleotide sequence is under the control of a functionally linked promotora.7. Live recombinant carrier micro-organism comprising a nucleotide sequence according to any of claims 3-5, or a nucleic acid according to item 6.8. An isolated antibody to1. Выделенный полипептид, содержащий аминокислотную последовательность, обладающий идентичностью аминокислотной последовательности более 53% с аминокислотной последовательностью SEQ ID NO:1, и/или обладающий идентичностью аминокислотной последовательности более 58% с аминокислотной последовательностью SEQ ID NO:3, где указанный полипептид способен индуцировать иммунный ответ п
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